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OCR: Yet on the primitive earth equal numbers of right and left- handed nucleotides would have been present When we put equal numbers of both kinds of nucleotides in our reaction mixtures, copying was inhibited All these problems are worrisome but they op not completely rule out the poss ibility that RNA was initially synthesized and replicated by relatively uncomplicated processes Perhaps minerals did indeed catalyze both the synthesis of properly structured nucleotides and their polymerization a random family of oligonucleotides Then copying without replication would have produced pair of complementary strands as Szostak has posited one of the strands happened to be ribozyme that could copy its complement and thus duplicate itself, the conditions needed for exponential replication of the two ...